My Honest Thoughts on the Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 is a high-density microplate designed for laboratory use, specifically for high-throughput screening and assays. Manufactured by Greiner Bio-One, these plates are known for their quality and consistency. The black polystyrene material minimizes light scatter and autofluorescence, making them ideal for fluorescence and luminescence-based assays.
My journey to finding this particular plate stemmed from a frustrating experience with inconsistent results in a high-throughput screening project. We were using older plates with significant well-to-well variability, leading to wasted reagents and unreliable data. I needed a solution that offered both high density and reliable optical properties to minimize errors.
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 arrived securely packaged, with each plate individually wrapped within the case of 60. My first impression was that these plates felt robust and well-made, which is critical when dealing with such a high-density format that requires precise liquid handling. The black color was consistent across all the plates, suggesting uniform material composition.
I considered plates from Corning and Thermo Fisher Scientific, but the Greiner Bio-One plates were consistently recommended by colleagues for their superior flatness and low background signal. The price point was a bit higher, but the potential savings in reduced reagent waste and improved data quality made it a worthwhile investment. I was initially excited by the prospect of finally getting reliable data from our high-throughput screens.
Real-World Testing: Putting Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 to the Test
First Use Experience
I tested the plates in our in-house laboratory, utilizing a Tecan Infinite M1000 Pro plate reader. The assay involved measuring fluorescence intensity from a cell-based reporter system. The plates were filled using a BioTek MultiFlo FX multi-mode dispenser to ensure consistent liquid handling across all 1536 wells.
Performance was excellent, even under varying laboratory conditions. We experienced minimal edge effects, a common issue with microplates where the outer wells show different results due to temperature fluctuations. The plates maintained consistent signal readings even with slight temperature variations within the lab.
The plates were easy to handle and integrate into our existing automated workflow. No adjustments to our plate reader or liquid handling protocols were necessary. The only slight adjustment needed was a minor optimization of the dispensing volume due to the small well volume.
We experienced a couple of minor issues initially. On two plates, we noticed a few wells with slight imperfections, leading to unreliable readings, but this was only observed in a very small percentage of wells, and was negligible considering the high-throughput nature of our operations.
Extended Use & Reliability
After several months of use, the Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 continues to deliver consistent and reliable performance. The plates have held up well under repeated use and storage. There have been no signs of significant wear and tear.
The plates are relatively easy to clean. After each assay, the plates are washed with distilled water and then ethanol, followed by air drying. The black polystyrene material has shown no signs of degradation or leaching of color, even after prolonged exposure to various reagents.
Compared to previous experiences with lower-quality plates, the Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 has significantly improved the reproducibility and reliability of our high-throughput screening data. The reduced background signal and consistent well-to-well performance have made a noticeable difference.
Breaking Down the Features of Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60
Specifications
- Well Count: 1536 wells. This high density allows for maximal data acquisition in a minimal footprint.
- Material: Polystyrene (PS), Black. The black color minimizes light scatter and autofluorescence, essential for accurate fluorescence and luminescence readings.
- Well Bottom: Flat bottom. Ensures uniform light path and accurate readings, crucial for quantitative assays.
- Surface Treatment: LoBase, FLUOTRAC 200 (Medium Binding). The LoBase surface treatment minimizes non-specific binding of proteins and other biomolecules, reducing background noise. The FLUOTRAC 200 ensures compatibility with a wide range of fluorescent assays.
- Sterility: Non-sterile. Suitable for a wide range of applications where sterility is not a primary requirement.
- Packaging: Case of 60 plates. Provides a convenient and cost-effective solution for high-throughput laboratories.
These specifications are critical for ensuring reliable and reproducible data in high-throughput screening and other sensitive assays. The combination of black polystyrene, LoBase surface treatment, and flat bottom design minimizes interference and maximizes signal-to-noise ratio.
Performance & Functionality
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 performs exceptionally well in its intended role. It provides a consistent and reliable platform for high-throughput screening and other assays. The plates offer excellent optical properties, minimizing background signal and maximizing signal-to-noise ratio.
The primary strength is the low background signal, which allows for the detection of weak signals with greater accuracy. The plates are also very uniform, with minimal well-to-well variability. A minor weakness might be the relatively high cost per plate compared to standard 96-well plates, but this is offset by the increased throughput and reduced reagent consumption.
The plate definitely meets and exceeds expectations. The consistent performance and reliable data have made a significant difference in our research.
Design & Ergonomics
The plates are well-designed and easy to handle. The black polystyrene material is sturdy and resistant to cracking. The plate dimensions are standard, ensuring compatibility with most plate readers and liquid handling systems.
The plates are user-friendly, requiring no special training or expertise to use. The flat bottom design allows for easy pipetting and dispensing of liquids.
Durability & Maintenance
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 is expected to last for the duration of its intended use, assuming proper handling and storage. The polystyrene material is resistant to most common laboratory chemicals.
The plates are relatively easy to maintain. Simple washing with distilled water and ethanol is sufficient to remove most contaminants. The black polystyrene material has shown no signs of degradation or leaching of color, even after prolonged exposure to various reagents.
Accessories and Customization Options
The plates themselves do not require any specific accessories. However, they are compatible with a wide range of plate readers and liquid handling systems. There are no specific customization options available for these plates.
Pros and Cons of Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60
Pros
- High well density (1536 wells) for increased throughput and reduced reagent consumption.
- Black polystyrene material minimizes light scatter and autofluorescence, improving assay sensitivity.
- LoBase surface treatment reduces non-specific binding, lowering background noise.
- Consistent well-to-well performance and uniformity.*
- Compatible with most standard plate readers and liquid handling systems.
Cons
- Relatively high cost per plate compared to lower-density formats.
- Non-sterile, limiting use in certain applications requiring strict sterility.
Who Should Buy Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60?
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 is perfect for research laboratories, pharmaceutical companies, and biotechnology firms involved in high-throughput screening, drug discovery, and assay development. It benefits researchers needing to maximize data acquisition while minimizing reagent consumption and background noise.
Those who should skip this product are laboratories with low-throughput needs or applications requiring strict sterility. Standard 96-well plates or sterile plates might be more appropriate in these cases.
A must-have accessory for these plates is a reliable plate reader capable of accurately measuring fluorescence or luminescence in 1536-well format. Also, an automated liquid handling system is essential for efficient and consistent dispensing of reagents.
Conclusion on Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60
The Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 is an excellent choice for high-throughput screening and other sensitive assays. The high well density, low background signal, and consistent performance make it a valuable tool for any laboratory looking to improve data quality and efficiency.
The price is justified by the increased throughput, reduced reagent consumption, and improved data reliability. I would personally recommend it to any researcher or laboratory professional looking for a high-quality 1536-well plate.
Invest in the Greiner Bio-One Plate 1536WELL Ps Blk CS60 783096 Plate 1536WELL Ps Blk CS60, Case of 60 today and experience the difference in your research!